mTOR inhibitor used off-label as a leading longevity intervention.
Typical dose range: 3–6 mg
Frequency: Weekly (most protocols)
Route: Oral
Half-life: ~60 hours
Evidence level: Strong in animals; off-label in longevity
The most extensively rodent-validated longevity drug. Dosing schedules in humans are still being optimised — work with a clinician.