5-HT3 antagonist — go-to for GLP-1 and titration nausea.
Typical dose range: 4–8 mg
Frequency: Up to 3x daily as needed
Route: Oral / sublingual
Half-life: ~4 hours
Evidence level: Strong (FDA-approved)
Won't fix the underlying cause but can rescue a rough titration day. QT-prolonging — don't stack with other QT drugs.