MK-677 (Ibutamoren)

Oral ghrelin mimetic that raises GH and IGF-1 around the clock.

Typical dose range: 10–25 mg

Frequency: Daily

Route: Oral

Half-life: ~24 h

Evidence level: Pre-clinical + anecdotal

Overview

Causes water retention and hunger. Watch fasting glucose — long-term use can impair insulin sensitivity.