Methylene Blue

Mitochondrial enhancer with nootropic and antioxidant effects at low doses.

Typical dose range: 0.5–4 mg/kg (low dose)

Frequency: Daily

Route: Oral

Half-life: ~5 h

Evidence level: Clinical (off-label)

Overview

Use only USP/pharmaceutical grade. Stay below 4 mg/kg to avoid the pro-oxidant zone. Avoid with SSRIs (serotonin syndrome risk).